1-嘧啶-2-基-[1,4]二氮杂环庚烷 - Names and Identifiers
1-嘧啶-2-基-[1,4]二氮杂环庚烷 - Physico-chemical Properties
Molecular Formula | C9H14N4
|
Molar Mass | 178.23 |
Density | 1.100±0.06 g/cm3(Predicted) |
Boling Point | 341.5±52.0 °C(Predicted) |
Flash Point | 160.3°C |
Vapor Presure | 8.03E-05mmHg at 25°C |
pKa | 9.99±0.20(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Air Sensitive |
Refractive Index | 1.537 |
MDL | MFCD06738258 |
1-嘧啶-2-基-[1,4]二氮杂环庚烷 - Risk and Safety
1-嘧啶-2-基-[1,4]二氮杂环庚烷 - Introduction
1-(2-Pyrimidinyl)homopiperazine is an organic compound with the chemical formula C9H13N3. It is a colorless to light yellow solid with an amino and heteropyrimidine ring structure similar to diazepane.
1-(2-Pyrimidinyl)homopiperazine has certain application value in the field of medicine. It is often used as an intermediate in central nervous system drugs for the synthesis of various hypnotic, anxiolytic and antipsychotic drugs. In addition, it can also be used as a stain for synthetic microscopy and cobalt oxydextran.
There are various methods for preparing 1-(2-Pyrimidinyl)homopiperazine. A commonly used synthetic method is the reaction of 2-amino-4-bromopyrimidine and bromoacetylacetone under alkaline conditions to give 1-(2-Pyrimidinyl)homopiperazine. The reaction is usually carried out in an anhydrous and oxygen-free environment, heating or refluxing the reaction. The product of the synthesis reaction needs to be separated and purified.
Regarding the safety information of 1-(2-Pyrimidinyl)homopiperazine, it is an organic compound with certain toxicity. Contact with the substance may cause irritation to the skin, eyes and respiratory system. Wear appropriate personal protective equipment during use and handling, and take care to avoid inhalation or contact with skin. In addition, it should be stored in a dry, cool and well-ventilated place, away from fire and oxidizing agents. Relevant safety procedures and precautions should be followed when using and handling the compound.
Last Update:2024-04-09 21:54:55